Six times per year, you will find here scientific
commentaries about asthma and asthma related topics.
ARLS
1999 N° 2 : Experts comments on 14 new subjects.
- Effects of
intranasal corticosteroids on adrenal, bone,
and blood markers of systemic activity in allergic
rhinitis
- Randomised, dose-ranging, placebo-controlled study of chimeric
antibody to CD4 (keliximab) in chronic
severe asthma
- Effect of
nebulized ipratropium on the hospitalization
rates of children with asthma
- Allergic
factors associated with the development of asthma
and the influence of cetirizine in a double-blind,
randomised, placebo-controlled trial: The rist results of
ETAC
- Classification
of asthma severity: should the international
guidelines be changed?
- Long-term
effects of inhaled corticosteroids in
chronic obstructive pulmonary disease: a meta-analysis
- The effects of regular inhaled formoterol, budesonide and
placebo on mucosal
inflammation and clinical indices in mild
asthma.
- Do inhaled
steroids cause osteoporosis?
- A comparison of two long-acting b-agonists, oral
bambuterol and inhaled salmeterol in the treatment of
moderate to severe asthmatic
patients with nocturnal symptoms
- Sex
differences in the use of asthma drugs:
Cross sectional study
- Comparison of 2.5 vs 7.5 mg of inhaled
albuterol in the treatment of acute asthma
- Classification of asthma severity: Should the
international guidelines be changed?
- The effects
of regular inhaled formeterol, budesonide,
and placebo on mucosal inflammation and clinical indices
in mild asthma
- Effect of differing doses of inhaled
budesonide on markers of airway inflammation
in patients with mild asthma
- Long term
effects of inhaled corticosteroids in COPD:
a meta analysis
- Dietary
anti oxidants and magnesium in type 1
brittle asthma: a case control study
ARLS
1999 N° 1 : Experts comments on 10 new subjects.
- Low-dose
formoterol Turbuhaler® (Oxis®) b.i.d., a
3-month placebo-controlled comparison with terbutaline
(q.i.d.)
- Salmeterol
prevents aspirin-induced attacks of asthma
and interferes with eicosanoid metabolism.
- Tolerability to high doses of formoterol and terbutaline
via Turbuhaler® for 3
days in stable asthmatic patients
- Fluticasone
propionate 750 µg/day versus beclomethasone
dipropionate 1500 µg/day: comparison of efficacy and
adrenal function in paediatric asthma
- Association of inhaled corticosteroid use with cataract
extraction in elderly patients
- Effect of
theophylline withdrawal on airway
inflammation in asthma
- Neuropharmacologic treatment of bronchial asthma with the
antidepressant
tianeptine: a double-blind, crossover
placebo-controlled study.
- Clinical
benefits and cost reduction associated with
a comprehensive asthma management programme at a managed
care organisation
- Long term
trends in quality of life from the FACET
study.
- A 15-year follow-up study of ventilatory
function in adults with asthma
ARLS 1998 N° 6 :
Experts comments on 9 new subjects. (December 1998)
- Effect of low-dose
beclomethasone dipropionate on asthma control and airway
inflammation
- Treatment of acute asthmatic
exacerbations
with an increased dose of inhaled steroid
- Clinical efficacy
of sublingual-swallow immunotherapy: a double-blind,
placebo-controlled trial of a standardised
five-grass-pollen extract in rhinitis
- Cost-effectiveness of fluticasone and
budesonide in
patients with moderate asthma
- Montelukast, a potent leukotriene receptor
antagonist, causes dose-related improvements in chronic
asthma
- Bambuterol is a
more cost-effective treatment than salmeterol in asthma
patients with nocturnal symptoms
- Effects of orally
inhaled budesonide in seasonal allergic rhinitis
- Randomised controlled trial
of inhaled
corticosteroids
in patients with chronic obstructive pulmonary disease
- Zafirlukast and
Churg-Strauss syndrome
ARLS 1998 N° 5 :
Experts comments on 8 new subjects. (October 1998)
- Comparative clinical study
of inhaled
beclomethasone dipropionate and triamcinolone acetonide in persistent asthma.
- Budesonide
delivered by Turbuhaler is effective in a dose-dependent
fashion when used in the treatment of adult patients with
chronic asthma
- Prednisolone in
acute childhood asthma: clinical responses to three
dosages
- Computer-based
models to
identify high-risk children with asthma
- Once-daily budesonide in mild
asthma
- Growth in
asthmatic children treated with fluticasone
propionate
- Dose-related response to inhaled fluticasone
propionate in
patients with methacholine-induced bronchial
hyperresponsiveness: a double-blind, placebo-controlled study
- Tolerance to the bronchoprotective
effect of salmeterol 12 hours after starting twice
daily treatment
ARLS 1998 N° 4 :
Experts comments on 7 new subjects. (July 1998)
- Duration of growth suppressive
effects of
regular inhaled corticosteroids
- Prospective, double-blind,
placebo-controlled, multicentre study on the effect
of high-dose, intravenous immunoglobulin in children and adolescents with
severe bronchial asthma.
- Pulmonary infiltrates,
eosinophilia, and cardiomyopathy following corticosteroid
withdrawal in patients with asthma receiving
zafirlukast
- Neuropsychological and behavioural
changes in asthmatic children treated with beclomethasone
diproprionate vs theophylline
- Short-term treatment with
budesonide does
not improve hyperresponsiveness to adenosine
5-monophosphate in COPD
- The US Lung Health Study
- Bone mineral density in children
with asthma
receiving long-term treatment with inhaled budesonide
ARLS 1998 N° 3 :
Experts comments on 7 new subjects. (May 1998)
- Prevalence of asthma symptoms, diagnosis and treatment in 12-14
year old children across Great Britain (International
study of asthma and allergies in childhood, ISAAC UK)
- Perinatal factors and atopic
disease in childhood
- Dose-related protection of exercise bronchoconstriction
by montelukast, a cysteinyl leukotriene-receptor
antagonist, at the end of a once-daily dosing interval
- A comparison of beclomethasone,
salmeterol and placebo in children with asthma
- Exercise-induced asthma
- Nebulized wet aerosol
treatment in emergency department - is it essential? Comparison
with large spacer device for metered-dose inhaler
- The leukotriene
receptor antagonist zafirlukast inhibits sulfur dioxide-induced
bronchoconstriction in patients with asthma
ARLS 1998 N° 2 :
Experts comments on 7 new subjects. (March 1998)
- The safety of asthma and
allergy in medications during pregnancy
- Effect of inhaled
formoterol and budesonide on exacerbations of asthma
- A
comparison of low-dose inhaled budesonide plus theophylline and
high-dose inhaled budesonide for moderate asthma
- A comparison between emergency
diagnostic and treatment unit (EDTU) and inpatient care in the
management of acute asthma
- Association between b 2-adrenoceptor polymorphism and susceptibility to
bronchodilator desensitisation in moderately severe
stable asthmatics
- Comparative lung delivery of
salbutamol given
via Turbuhaler and Diskus dry powder inhaler devices
- Esophageal candidiasis as a complication of inhaled
corticosteroids
ARLS 1998 N° 1 :
Experts comments on 8 new subjects. (January 1998)
- A patient preference study comparing
Turbuhaler with Diskus, two multi-dose dry powder
inhaler devices
- Results of the first
U.S. double-blind, placebo-controlled, multicenter
clinical study in
asthma with pranlukast, a novel leukotriene receptor
antagonist
- Nebulized
salbutamol with and without ipratropium bromide in the treatment of acute asthma.
- A 1-year,
placebo-controlled, double-blind house-dust-mite
immunotherapy study in asthmatic adults
- Effects of high
dose intravenous immunoglobulin in two severe corticosteroid
insensitive asthmatic patients
- Is
asthma treatment affordable in developing countries ?
- A national estimate of the
economic costs of asthma
- Improvement of bronchial
hyperresponsiveness in asthmatic children treated for
concomitant sinusitis
.
ARLS 1997 N° 6 : Experts comments on 6
new subjects.
- Osteoporotic
vertebral fractures in a man under highdose inhaled
glucocorticoid therapy
- Use of inhaled
corticosteroids
and the risk of cataracts
- A randomized, double-blind
dose reduction study to compare the minimal effect of
dose of budesonide Turbuhaler and
fluticasone proionate Diskhaler.
- Pranlukast, a novel
leukotriene receptor antagonist: results of the first European,
placebo controlled, multicentre clinical study asthma
- Salmeterol. A review of its pharmacological
properties and clinical efficacy in the management of
children with asthma
- The use of serum
eosinophil cationic protein (ECP) in the management of steroid
therapy in chronic asthma.
ARLS 1997 N° 5 :
Experts comments on 7 new subjects.
- Inhibition of allergen-induced
airway obstruction and leukotriene generation in
atopic asthmatic subjects by the leukotriene biosynthesis
inhibitor BAYx1005
- Effect of long term treatment
with salmeterol on asthma control: a double blind,
randomised crossover study.
- The role of cockroach allergy
and exposure to cockroach allergen in causing morbidity
among inner-city children with asthma.
- Adult patients may outgrow their asthma. A 25 year follow-up study
- The role of cockroach allergy and exposure to cockroach
allergen in causing morbidity
among inner-city children with asthma.
- Leukotriene antagonist
prevents exacerbation of asthma during reduction of
high-dose inhaled corticosteroid
- Suppression of the immune system by oral glucocorticoid therapy in
bronchial asthma
ARLS 1997 N° 4 :
Experts comments on 7 new subjects.
- Inhaled steroids and the risk
of hospitalization for asthma
- A controlled trial of
immunotherapy for asthma in allergic children
- Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate
asthma: a randomized, double-blind, placebo-controlled
trial
- Impact of nurse-led home
management training programme in children admitted to
hospital with acute asthma: a ramdomised controlled
study.
- Montelukast causes prolonged,
potent leukotriene D4-receptor antagonism in the airways
of patients with asthma
- The clinical efficacy of
combination nebulized anticholinergic and adrenergic
bronchodilators vs nebulized adrenergic bronchodilator in
acute asthma
- Adrenal suppression with chronic dosing of fluticasone propionate compared with
budesonide in adult astmatic patients
ARLS 1997 N° 3 :
Experts comments on 8 new subjects.
- Effect of multiple actuations, delayed inhalation and
antistatic treatment on the lung
bioavailability of salbutamol via a spacer device
- Bronchodilators and acute
cardiac death
- Adult asthma and
gastro-oesophageal reflux: the effects of omeprazole
therapy on asthma
- Dose-response of inhaled
drugs in asthma: an update
- An inhaled glucocorticoid does not prevent tolerance to
the bronchoprotective effect
of a long-acting inhaled b2-agonist
- Knemometry, urine cortisol excretion, and measures of the
insulin-like growth factor axis and collagen turnover in children treated with inhaled
glucocorticosteroids
- Comparison of short courses of oral
prednisolone and fluticasone propionate in the
treatment of adults with acute exacerbations of asthma in
primary care
- Changes in bone markers in
children with asthma during inhaled budesonide and
nedocromil treatments
ARLS 1997 N° 2 :
Experts comments on 5 new subjects.
- Effectiveness of fluticasone
propionate
- Comparison of budesonide via
Turbohaler and fluticasone propionate via disc-inhaler
- The effect of the menstrual
cycle on asthma presentations in the emergency department
- Effects of prednisolone on
bone turnover in patients with corticosteroid resistant
asthma
- A risk-benefit assessment of
methotrexate in cortico-steroid dependent asthma
Astra Respiratory Literature
Service : Experts Comments on :
- A 12-week dose-ranging study of fluticasone propionate powder in the treatment of asthma
- Use of oral corticosteroids in the
community and the prevention of secondary osteoporosis: a cross sectional study
- A placebo-controlled multicenter study of auranofin in the treatment of patients with
corticosteroid-dependent asthma
- Effects of theophylline on inflammatory cells and cytokines in
asthmatic subjects: a placebo-controlled parallel group
study
- Effects of regular salmeterol on lung function and exercise capacity in
patients with chronic obstructive airways disease
- Asthma treatment in pregnancy: a randomized controlled study
Inhibition of NF-kappaB
by sodium salicylate and aspirin.
comment by Dany
JAFFUEL, Montpellier France
Allergology and asthma
Québec 1996 : Tabagisme
(PM Renzi) , Corticostéroïdes
inhalés (L. Blais), (L-P. Boulet),
Asthme Professionnel (L. Perfetti),
Asthme Infantil (D. Gautrin):
Communications de la réunion annuelle conjointe des 3,4 et 5
octobre 1996 
Allergy to latex Prevalence of latex
sensitization in a general population 
D. Vervloet
Churg&Strauss Asthma
Ph. Godard
Food Allergy &
Pediatric asthma 
MENARDO J.L Hôpital Arnaud de Villeneuve,
MONTPELLIER FRANCE
Eicosanoids, Aspirin and
Asthma Coordinating Center Department of Medicine
University School of Medicine 31 066 Krakow, ul. Skawinska 8,
Poland
A. Szczeklik (Krakow) 
Epithelium
and asthma (
<=version française) (english version =>
)
Ph. Godard, P. Chanez
Gènes et Allergie :
Existe-t-il des gènes candidats à l'allergie ? 
Pascal Demoly
, Jean Bousquet, Philippe Godard,
François-Bernard Michel
Bronchial Asthma :
Considerations in asthma and concomitant 
upper airway symptoms - Ph Godard
...